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Phytochemical and
pharmacological studies on Orthosiphon stamineus Benth. (Lamiaceae)
hydroalcoholic extracts.
Olah NK, Radu L, Mogosan
C, Hanganu D, Gocan S.
SC PLANTEXTRAKT SRL, 3462-Radaia,
Cluj, Romania. neliolah@yahoo.com
The main components of
Orthosiphon stamineus Benth. leaves and extracts are the
pharmacologically active polyphenols: the polymethoxylated flavonoids
and the caffeic acid derivatives. Two tinctures, having different
alcohol concentration, were studied from phytochemical and
pharmacological point of view. The main polyphenols were identified and
quantitatively determined by HPLC. Comparison of the retention
parameters and UV-Vis spectra of standards and those of the separated
compounds performed the identification of caffeic-, cichoric- and
rosmarinic acids, respectively, of sinesetine and eupatorine. The
quantitative determination was performed by external standard method.
The diuretic, saluretic and uricosuric actions of the studied tinctures
were compared by experiments on rats.
PMID: 12946538 [PubMed -
indexed for MEDLINE]
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